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History

We are a leading company of IV solutions in Japan. Our history is the very history of the development of Japanese IV products. We are committed to being the best partner of patients and healthcare professionals in the field of clinical nutrition.

Note: All products in this table below are sold by Otsuka Pharmaceutical Factory and other Otsuka Group companies. Generally, product names are those currently used. Product photos are generally those at the time of launch.

2008
ARTCEREB irrigation and perfusion solution for cerebrospinal surgery launched
Otsuka Holdings Co., Ltd. established
Urepearl Plus Lotion 10 launched—a medicine for the treatment of dry skin with improved formulation, effect and use sensation
2009
Innerpower, beverage (jelly), launched
Oral rehydration solution OS-1 Powder launched—a powder type that is convenient for carrying around
ELNEOPA No. 1/No. 2 Injection launched—a TPN formulation containing glucose, electrolytes, amino acids, multiple vitamins, and trace elements
HINE Jelly Aqua launched—a concentrated liquid diet with added water
2010
BICANATE Injection launched—a bicarbonated Ringer’s solution
Otsuka Holdings Co., Ltd. listed on the First Section of the Tokyo Stock Exchange
2011 Sodium Phosphate Corrective Injection 0.5 mmol/mL launched—a corrective electrolyte solution
RACOL-NF Liquid for Enteral Use, a low residual diet preparation (for feeding tube and oral administration), and Twinline-NF Liquid for Enteral Use, an elemental diet preparation, launched
Diatranz Otsuka Limited established in New Zealand
2012 Oral rehydration solution OS-1 Powder approved as food for persons with medical conditions (individually evaluated type) categorized as food for special dietary use by the Consumer Affairs Agency
2013
Voluven 6% Solution for Infusion launched - a plasma substitute
Capital participation in Claris Otsuka Private Limited (currently Otsuka Pharmaceutical India Private Limited)
2014 ENGELEAD Apple Jelly and ENGELEAD Grape Jelly approved as a food for special dietary use, food for persons who have difficulty swallowing (approval standardⅠ) by the Consumer Affairs Agency
HINE E-Gel launched—a concentrated liquid diet that changes state from liquid to gel form in reaction with stomach acids
Povidone-iodine Solution 10% Antiseptic Applicator Otsuka 10 mL/25 mL launched—an external-use antiseptic
RACOL-NF SemiSolid for Enteral Use launched—an enteral nutrient solution
Shinichi Ogasawara appointed President
Acquired a local pharmaceutical company in Egypt as a subsidiary (currently Otsuka Al-Obour Pharmaceutical Egypt S.A.E.)
PROCESS LEAD launched—a chew and swallow managing food that takes into account physical properties after chewing
2015 Lilium Otsuka Co., Ltd. established
Olanedine Antiseptic Solution 1.5% and Olanedine Solution 1.5% Antiseptic Applicator launched—an external-use antiseptic
2016
Lilium α-200 launched - an ultrasound bladder imaging device
2017
ELNEOPA-NF No. 1/No. 2 Injection launched—a TPN formulation containing glucose, electrolytes, amino acids, multiple vitamins, and trace elements
HINE Jelly, and HINE Jelly AQUA—a concentrated liquid diet, approved as comprehensive nutritional food for patients [zinc adjustment] categorized as food for special dietary use by the Consumer Affairs Agency
Rebamipide tablets 100mg Otsuka launched - an anti-gastritis and anti-gastric ulcer agent
HINEX REHADAYS launched—a beverage to support exercise and rehabilitation
2019
ENORAS Liquid for Enteral Use (for feeding tube and oral administration) launched
Cellstor-S cell suspension and preservation solution and Cellstor-W cell wash and preservation solution launched
HINE E-Gel LC launched—a concentrated liquid diet product
2020
Oral care gel (medicated toothpaste) HINORA (quasi-drug) and oral moisture gel HINORA Moisture Gel (oral cosmetic) launched
Oral rehydration solution OS-1 series approved for new labeling including “prevention of deterioration of or recovery from dehydration” and “heatstroke with dehydration” as individually evaluated food for persons with medical conditions, categorized as food for special dietary use by the Consumer Affairs Agency
VISCOCLEAR launched―gel to secure the visual field that is used for the endoscope for natural opening
ENEFLUID Injection launched―an amino acid, carbohydrate, electrolyte, fat, and water-soluble vitamin injection
2021
HINEX E-Gel and HINEX E-gel LC launched― concentrated liquid diet products, as new products with changed names and some compositions
Otsuka Gypto Pharmaceutical Egypt S.A.E. established in Egypt
2022
Actreen launched—an intermittent urological catheter
Tolvaptan OD tablets 7.5/15 mg Otsuka launched―a vasopressin V2-receptor antagonist
Lilium IP200 launched—an ultrasound bladder imaging device
Pokenyu (Pocket Nutrition) service begun—a cloud service that helps professionals involved in home medical care identify and solve dietary and nutritional issues for home medical care patients
OS-1 Apple Flavor added to the Oral Rehydration Solution OS-1 series
OT-Balloon Catheter launched—an intermittent urological catheter
2023
Lilium one launched— a medical device that measures urine volume in the bladder specialized for single measurement